73387-56-1

Basic information

• Product Name: 1H-Pyrazole, 1-methyl-5-(4-methylphenyl)-
• CAS NO: 73387-56-1
• Molecular Formula: C11H12N2
• Molecular Weight: 172.23
• Mol File: 73387-56-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole, 1-methyl-5-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole, 1-methyl-5-(4-methylphenyl)-(73387-56-1)
• EPA Substance Registry System: 1H-Pyrazole, 1-methyl-5-(4-methylphenyl)-(73387-56-1)

Safety Data

• Hazardous Substances Data: 73387-56-1(Hazardous Substances Data)

Upstream product

• 1239016-73-9 3-(4-methylphenyl)-N,N-dipropylprop-2-yn-1-amine 
• 60-34-4 methylhydrazine 
• 766-97-2 4-n-methylphenylacetylene 
• 930-36-9 1-methyl-1H-pyrazole 
• 106-38-7 para-bromotoluene 
• 720702-41-0 (1-methyl-1H-pyrazol-5-yl)boronic acid 

Downstream Products

• 1394034-47-9 2-bromo-1-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]ethanone 
• 1394034-46-8 1-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]ethanone 
• 1394034-48-0 N-{2-methyl-4-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-1H-imidazol-1-yl}acetamide 
• 1394034-49-1 2-methyl-4-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-1H-imidazol-1-amine 
• 1394034-50-4 N-{2-methyl-4-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-1H-imidazol-1-yl}imidoformamide 
• 1394034-51-5 7-methyl-5-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]imidazo[5,1-f][1,2,4]triazin-4(3H)-one 
• 1394034-52-6 7-methyl-5-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-4-(1H-1,2,4-triazol-1-yl)imidazo[5,1-f][1,2,4]triazine 
• 1394033-53-4 4-(azetidin-1-yl)-7-methyl-5[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]imidazo[5,1-f][1,2,4]triazine 
• 689250-61-1 1-methyl-5-(p-tolyl)-1H-pyrazole-4-carbaldehyde 
• 1415637-99-8 (4,6-dichloropyrimidin-5-yl)(1-methyl-5-(p-tolyl)-1H-pyrazol-4-yl)methanone 
• 1415638-00-4 (4,6-dichloropyrimidin-5-yI)[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yI]methanone 
• 1415637-38-5 4-(azetidin-1-yl)-1-methyl-3-(1-methyl-5-(p-tolyl)-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 1390637-82-7 CYP₃cide 
• 1415638-19-5 {4-chloro-6-[(3S)-3-(piperidin-1-yl)pyrrolidin-1-yl]pyrimidin-5-yl}[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]methanone 

Relevant articles and documents

Regioselective palladium-catalyzed C–H arylation of 4-alkoxy and 4-thioalkyl pyrazoles

A methodology for the palladium-catalyzed regioselective C–H arylation of electron rich pyrazoles has been developed. New ligands and mild conditions (70–90 °C) have been identified for this transformation. An intramolecular application of the methodology provided a novel synthetic route for the regioselective synthesis of 1,5-dihydroisochromeno[4,3-c]pyrazoles and 1,5-dihydroisothiochromeno[4,3-c]pyrazoles.

Palladium-catalysed direct diarylations of pyrazoles with aryl bromides: A one step access to 4,5-diarylpyrazoles

The palladium-catalysed direct arylation of pyrazoles with aryl halides, using PdCl(C3H5)(dppb)/KOAc catalyst, reveals a similar reactivity of C4 and C5 CH bonds of pyrazoles, whereas the C3 CH bond is almost unreactive, and gives ac

PYRAZOLO[3,4-D]PYRIMIDINE COMPOUNDS AND THEIR USE AS PDE2 INHIBITORS AND/OR CYP3A4 INHIBITORS

The present invention provides, inter alia, compounds of Formula (I) and pharmaceutically acceptable salts thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds as a method for the treatment of a disease or condition selected from the group consisting of central nervous system disorders, cognitive disorders, schizophrenia, dementia and other disorders in a mammal. The present invention further provides compounds of Formula (Id) and pharmaceutically acceptable salts thereof as CYP3A4 selective inhibitors.