1239346-72-5Relevant academic research and scientific papers
KMnO4-mediated oxidation as a continuous flow process
Sedelmeier, Joerg,Ley, Steven V.,Baxendale, Ian R.,Baumann, Marcus
supporting information; experimental part, p. 3618 - 3621 (2010/11/17)
An efficient and easily scalable transformation of alcohols and aldehydes to carboxylic acids and nitroalkane derivatives to the corresponding carbonyls and carboxylic acids using permanganate as the oxidant within a continuous flow reactor is reported. Notably, the generation and downstream processing of MnO2 slurries was not found to cause any blocking of the reactor when ultrasound pulses were applied to the flow system.
