1239363-40-6

Basic information

• Product Name: 1-Cyclopropyl-4-iodo-1H-pyrazole
• Synonyms: 1-Cyclopropyl-4-iodo-1H-pyrazole
• CAS NO: 1239363-40-6
• Molecular Formula: C₆H₇IN₂
• Molecular Weight: 234.03765
• EINECS: -0
• Mol File: 1239363-40-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 1-Cyclopropyl-4-iodo-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclopropyl-4-iodo-1H-pyrazole(1239363-40-6)
• EPA Substance Registry System: 1-Cyclopropyl-4-iodo-1H-pyrazole(1239363-40-6)

Safety Data

• Hazardous Substances Data: 1239363-40-6(Hazardous Substances Data)

Usage

Uses

1-Cyclopropyl-4-iodo-1H-pyrazole is a useful chemical for the preparation of dihydropyridinone MGAT2 inhibitor.

Upstream product

• 1151814-36-6 1-cyclopropylpyrazole 
• 3469-69-0 4-iodopyrazole 
• 4333-56-6 cyclopropyl bromide 
• 411235-57-9 cyclopropylboronic acid 

Downstream Products

• 1151802-22-0 1-cyclopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 

Relevant articles and documents

Synthesis of NVS-BPTF-1 and evaluation of its biological activity

BPTF (bromodomain and PHD finger containing transcription factor) is a multidomain protein that plays essential roles in transcriptional regulation, T-cell homeostasis and stem cell pluripotency. As part of the chromatin remodeling complex hNURF (nucleoso

HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

DIHYDROPYRIDINONE MGAT2 INHIBITORS FOR USE IN THE TREATMENT OF METABOLIC DISORDERS

The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (MGAT2) inhibitors which may be used as medicaments.