1239460-82-2

Basic information

• Product Name: 5,6-DibroMothieno[2,3-d]pyriMidin-4(3H)-one
• Synonyms: 5,6-DibroMothieno[2,3-d]pyriMidin-4(3H)-one
• CAS NO: 1239460-82-2
• Molecular Formula: C6H2Br2N2OS
• Molecular Weight: 309.96588
• Mol File: 1239460-82-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5,6-DibroMothieno[2,3-d]pyriMidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-DibroMothieno[2,3-d]pyriMidin-4(3H)-one(1239460-82-2)
• EPA Substance Registry System: 5,6-DibroMothieno[2,3-d]pyriMidin-4(3H)-one(1239460-82-2)

Safety Data

• Hazardous Substances Data: 1239460-82-2(Hazardous Substances Data)

Upstream product

• 4651-82-5 2-amino-3-cyanothiophene 
• 14080-50-3 thieno[2,3-d]pyrimidin-4(3H)one 

Downstream Products

• 1239460-84-4 5-bromo-4-hydrazinylthieno[2,3-d]pyrimidine 
• 814918-95-1 5-bromo-4-chlorothieno[2,3-d]pyrimidine 

Relevant articles and documents

Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration

The SAR of a series of brain penetrant, trisubstituted thiophene based JNK inhibitors with improved pharmacokinetic properties is described. These compounds were designed based on information derived from metabolite identification studies which led to compounds such as 42 with lower clearance, greater brain exposure and longer half life compared to earlier analogs.