1239669-98-7

Upstream product

• 343338-28-3 (S)-2-methylpropane-2-sulfinamide 
• 87310-69-8 N-(4-cyano-3-trifluoromethyl-phenyl)-2-oxo-propionamide 

Downstream Products

• 1373493-06-1 (S(S),S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-(-1,1-dimethylethylsulfinamido)-3-(4-fluorophenylsulfonyl)-2-methylpropanamide 
• 1373493-14-1 [S(S),S]-(tert-butylsulfinyl)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-methylziridine-2-carboxamide 
• 1373493-11-8 [S(S),R]-(tert-butylsulfinyl)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-methylziridine-2-carboxamide 
• 1239670-03-1 (S)-4-(4-((4-cyanophenoxy)methyl)-4-methyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile 
• 1239669-89-6 (S)-2-amino-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-methylpropanamide 
• 1373493-15-2 [S(S),S]-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-cyanophenoxy)-2-((S)-1,1-dimethylethylsulfinamido)-2-methylpropanamide 
• 1373493-13-0 C₁₈H₁₅F₄N₃OS 
• 1373493-12-9 C₂₂H₂₃F₄N₃O₂S₂ 
• 1373493-10-7 (S)-4-(4-((4-fluorophenylsulfonyl)methyl)-4-methyl-5-oxo-2-thioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile 
• 1239670-13-3 (S)-4-(4-((4-fluorophenylsulfonyl)methyl)-4-methyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoro methyl)benzonitrile 
• 1239670-11-1 (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-fluorophenylsulfonyl)-2-methyl-2-(4-methylphenylsulfonamido)propanamide 
• 1239670-12-2 (S)-2-amino-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-fluorophenylsulfonyl)-2-methyl propanamide 
• 1239670-14-4 (S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-(1,1-dimethylethylsulfonamido)-3-(4-fluorophenyl sulfonyl)-2-methylpropanamide 

Relevant academic research and scientific papers

Nonsteroidal androgen receptor ligands: Versatile syntheses and biological data

We report herein a stereoselective and straightforward methodology for the synthesis of new androgen receptor ligands with (anti)-agonistic activities. Oxygen-nitrogen replacement in bicalutamide-like structures paves the way to the disclosure of a new class of analogues, including cyclized/nitrogen-substituted derivatives, with promising antiandrogen (or anabolic) activity.