123983-06-2

Usage

Chemical class

Phenolic compound with an amine group and a propyl chain

Physical state

Colorless to pale yellow liquid at room temperature

Odor

Faint amine-like

Medicinal properties

Antihistamine, analgesic, potential anti-inflammatory and anti-cancer properties

Industrial applications

Production of dyes, perfumes, and other organic compounds

Safety precautions

Potential for skin and eye irritation, can cause respiratory issues if inhaled

Upstream product

• 610-99-1 1-(2-Hydroxy-phenyl)-propan-1-on 
• 7664-41-7 ammonia 
• 1247949-41-2 2-(1-iminopropyl)phenol 
• 1422447-36-6 2-(1-p-tosylpropyl)phenol 
• 1441-87-8 salicyloyl chloride 
• 19311-91-2 N,N-diethylsalicylamide 

Downstream Products

• 73758-02-8 (1R,4aS,10aR)-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,5,6,7,8,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid [1-(2-hydroxy-phenyl)-propyl]-amide 

Relevant academic research and scientific papers

Direct amination of 2-(1-tosylalkyl)phenols with aqueous ammonia: A metal-free synthesis of primary amines

A metal-free and concise method for the selective synthesis of primary amines directly from 2-(1-tosylalkyl)phenols with aqueous ammonia under mild conditions has been developed. In addition, primary amine could be conveniently converted to benzoxazinone in good yield.

Chiral phosphoric acid-catalyzed enantioselective transfer hydrogenation of ortho-hydroxyaryl alkyl N - H ketimines

The first enantioselective chiral phosphoric acid-catalyzed transfer hydrogenation of unprotected ortho-hydroxyaryl alkyl N - H ketimines using Hantszch di-tert-butyl ester as a reductant is reported. A variety of ortho-hydroxybenzylamines were obtained in good to excellent yields and enantiomeric excesses.