1239897-47-2Relevant academic research and scientific papers
A comparative study of the catalytic activity of nanosized oxides in the one-pot synthesis of highly substituted dihydropyridines
Safaei-Ghomi, Javad,Heidari-Baghbahadorani, Elham,Shahbazi-Alavi, Hossein,Asgari-Kheirabadi, Mehrnoosh
, p. 18145 - 18152 (2015)
A four-component reaction of aromatic aldehydes, ethyl cyanoacetate, arylamines, and dimethyl acetylenedicarboxylate has been achieved in the presence of nanosized oxides (ZnO NPs, CuO NPs, CeO2 NPs, SnO NPs, MgO NPs and CaO NPs) as highly effe
Synthesis of polysubstituted dihydropyridines by four-component reactions of aromatic aldehydes, malononitrile, arylamines, and acetylenedicarboxylate
Sun, Jing,Xia, Er-Yan,Wu, Qun,Yan, Chao-Guo
supporting information; experimental part, p. 3678 - 3681 (2010/10/03)
A practical and efficient procedure for the preparation of the polysubstituted dihydropyridines was developed through a unique four-component reaction of aromatic aldehydes, malononitrile, arylamines, and acetylenedicarboxylate in ethanol in the presence of triethylamine as a base promoter. This four-component reaction is atom-efficient, high-yielding, and applicable to a wide variety of four-component reactions.
