124005-64-7Relevant academic research and scientific papers
NUCLEOPHILIC SUBSTITUTION OF PENTAFLUOROBENZENES WITH IMIDAZOLE
Fujii, Shozo,Maki, Yasuo,Kimoto, Hiroshi
, p. 131 - 144 (1989)
The imidazole substitution of pentafluorobenzenes (C6F5R : R = CN, NO2, CO2C2H5, CHO, I, Br, Cl, H) occurred mainly at the para-position to R and corresponding 1-(4'-R-tetrafluorophenyl)imidazoles were obtained in good yields.The reactivity varied markedly with the substituents: nitro- or cyanopentafluorobenzene easily reacted at ambient temperature without any bases; however, methyl- or methoxypentafluorobenzene failed to react even at 100 degC in the presence of a strong base.
