124006-23-1

Basic information

• Product Name: BUTYL-(2,4-DIMETHOXY-PHENYL)-AMINE
• Synonyms: BUTYL-(2,4-DIMETHOXY-PHENYL)-AMINE
• CAS NO: 124006-23-1
• Molecular Formula: C₁₂H₁₉NO₂
• Molecular Weight: 209.28476
• Mol File: 124006-23-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 310.8°C at 760 mmHg
• Flash Point: 128.4°C
• Appearance: /
• Density: 1.013g/cm³
• Vapor Pressure: 0.000588mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: BUTYL-(2,4-DIMETHOXY-PHENYL)-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: BUTYL-(2,4-DIMETHOXY-PHENYL)-AMINE(124006-23-1)
• EPA Substance Registry System: BUTYL-(2,4-DIMETHOXY-PHENYL)-AMINE(124006-23-1)

Safety Data

• Hazardous Substances Data: 124006-23-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H19NO2/c1-4-5-8-13-11-7-6-10(14-2)9-12(11)15-3/h6-7,9,13H,4-5,8H2,1-3H3

Upstream product

• 17715-69-4 1-Bromo-2,4-dimethoxybenzene 
• 109-73-9 N-butylamine 
• 36896-61-4 2,4-dimethoxyphenyllead triacetate 

Relevant articles and documents

Amino acid promoted CuI-catalyzed C-N bond formation between aryl halides and amines or N-containing heterocycles

CuI-catalyzed coupling reaction of electron-deficient aryl iodides with aliphatic primary amines occurs at 40 °C under the promotion of N-methylglycine. Using L-proline as the promoter, coupling reaction of aryl iodides or aryl bromides with aliphatic primary amines, aliphatic cyclic secondary amines, or electron-rich primary arylamines proceeds at 60-90 °C; an intramolecular coupling reaction between aryl chloride and primary amine moieties gives indoline at 70 °C; coupling reaction of aryl iodides with indole, pyrrole, carbazole, imidazole, or pyrazole can be carried out at 75-90 °C; and coupling reaction of electron-deficient aryl bromides with imidazole or pyrazole occurs at 60-90 °C to provide the corresponding N-aryl products in good to excellent yields. In addition, N,N-dimethylglycine promotes the coupling reaction of electron-rich aryl bromides with imidazole or pyrazole to afford the corresponding N-aryl imidazoles or pyrazoles at 110 °C. The possible action of amino acids in these coupling reactions is discussed.

ARYLATION OF AMINES BY ARYLLEAD TRIACETATES USING COPPER CATALYSIS.

The selective monoarylation of aliphatic, heterocyclic and aromatic amines has been performed with a variety of aryllead triacetates 1-4 under copper diacetate catalysis.