124016-65-5Relevant academic research and scientific papers
A SHORT AND EFFICIENT SYNTHESIS OF (+/-)-ISORETRONECANOL AND (+/-)-TRACHELANTHAMIDINE
Cabezas, Nieves,Thierry, Josiane,Potier, Pierre
, p. 607 - 610 (2007/10/02)
Radical decarboxylation of N-protected proline in the presence of dimethyl fumarate gave a thiopyridyl adduct 5 which was readily transformed into isoretronecanol 1 and trachelanthamidine 2.
MANIPULATION OF THE CARBOXYL GROUPS OF α-AMINO-ACIDS AND PEPTIDES USING RADICAL CHEMISTRY BASED ON ESTERS OF N-HYDROXY-2-THIOPYRIDONE
Barton, Derek H. R.,Herve, Yolande,Potier, Pierre,Thierry, Josiane
, p. 5479 - 5486 (2007/10/02)
Photolysis of α-amino-acid or peptide esters derived from N-hydroxy-2-thiopyridone in the presence of t-butylthiol affords the expected decarboxylation products in good yield.The reaction can be applied to the α-carboxyl or to the side chain carboxyl of g
