124033-84-7Relevant academic research and scientific papers
Palladium(II)-Promoted Cross-Coupling of 4-Alkenyl-2-azetidinones with Organomercurials
Larock, Richard C.,Ding, Shuji
, p. 2081 - 2085 (2007/10/02)
The palladium-promoted cross-coupling of 4-alkenyl-2-azetidinones with aryl and vinylic mercurials provides 5-aryl-3-alkenamides and 3,6-alkadienamides, respectively.Modest to excellent stereoselectivity for formation of the new carbon-carbon double bond is observed.The reaction becomes catalytic in palladium when cupric chloride and oxygen are introduced.This process constituted the first organometallic ring opening of 2-azetidinones to acyclic unsaturated amides.
Synthesis of aryl-substituted 3-alkenamides via palladium-catalyzed cross-coupling of aryl iodides and 4-alkenyl-2-azetidinones
Larock,Ding
, p. 979 - 982 (2007/10/02)
Palladium catalyzes the cross-coupling of aryl iodides and 4-alkenyl-2-azetidinones to give good yields of aryl-substituted 3-alkenamides.
