1240371-95-2

Upstream product

• 216958-25-7 1-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine 
• 216958-27-9 1-(2-deoxy-1-D-ribofuranosyl)-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine 
• 187479-00-1 (2R,3S,5R)-5-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol 
• 871-84-1 1,7-Octadiyne 
• 1240372-03-5 1-[2-deoxy-β-D-erythropentofuranosyl]-3-(octa-1,7-diyn-1-yl)-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine 
• 1240372-02-4 1-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythropentofuranosyl]-3-(octa-1,7-diyn-1-yl)-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine 
• 1240371-94-1 1-[2-deoxy-β-D-erythropentofuranosyl]-3-(octa-1,7-diyn-1-yl)-4-{[(N,N-dimethylamino)methylidene]amino}-1H-pyrazolo[3,4-d]pyrimidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Downstream Products

• 1240371-96-3 1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-erythropentofuranosyl]-4-{[(N,N-dimethylamino)methylidene]amino}-3-(octa-1,7-diyn-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-3'-(2-cyanoethyl)-N,N-diisopropylphosphoramidite 

Relevant academic research and scientific papers

Azide - Alkyne "click" conjugation of 8-aza-7-deazaadenine-DNA: Synthesis, duplex stability, and fluorogenic dye labeling

The internal dye labeling of DNA by the Huisgen-Meldal-Sharpless "click" reaction is described. Fluorogenic 9-azidomethyl anthracene 2 and 3-azido-7-hydroxycoumarin 3 were employed in the postsynthetic functionalization of oligonucleotides incorporating o