1240372-00-2

Upstream product

• 871-84-1 1,7-Octadiyne 
• 187479-00-1 (2R,3S,5R)-5-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol 
• 622-79-7 benzyl azide 
• 216958-25-7 1-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythro-pentofuranosyl]-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine 
• 216958-27-9 1-(2-deoxy-1-D-ribofuranosyl)-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine 
• 1240372-03-5 1-[2-deoxy-β-D-erythropentofuranosyl]-3-(octa-1,7-diyn-1-yl)-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine 
• 1240372-02-4 1-[2-deoxy-3,5-di-O-(p-toluoyl)-β-D-erythropentofuranosyl]-3-(octa-1,7-diyn-1-yl)-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine 

Relevant academic research and scientific papers

Hydrogelation and spontaneous fiber formation of 8-aza-7-deazaadenine nucleoside 'click' conjugates

Nucleoside hydrogels based on benzyl azide 'click' conjugates of 8-aza-7-deaza-2′-deoxyadenosine bearing 7-ethynyl, 7-octa-(1,7-diynyl), and 7-tri-prop-2-ynyl-amine side chains were synthesized (1, 3, 4). The cycloaddition adduct with the shortest linker

Azide - Alkyne "click" conjugation of 8-aza-7-deazaadenine-DNA: Synthesis, duplex stability, and fluorogenic dye labeling

The internal dye labeling of DNA by the Huisgen-Meldal-Sharpless "click" reaction is described. Fluorogenic 9-azidomethyl anthracene 2 and 3-azido-7-hydroxycoumarin 3 were employed in the postsynthetic functionalization of oligonucleotides incorporating o