124040-41-1Relevant articles and documents
General Method for the Synthesis of 2'-Azido-2',3'-dideoxynucleosides by the Use of -Hydride Shift and &β-Elimination Reactions
Kawana, Masajiro,Kuzuhara, Hiroyoshi
, p. 469 - 478 (2007/10/02)
The title nucleoside (16U, C, G and H) were synthesized from pyrimidine and purine ribonucleosides in about 30percent overall yield in 6 steps via key intermediates, protected 3'-deoxy-arabino-nucleosides, which were obtained by deoxygenative -hydrid
SYNTHESIS OF 2'- AND 3'-AZIDO-2',3'-DIDEOXYADENOSINES. PREPARATIVE APPLICATIONS OF THE DEOXYGENATIVE-HYDRIDE SHIFT AND β-ELIMINATION REACTIONS OF O-SULFONYLATED ADENOSINES
Kawana, Nasajiro,Kuzuhara, Hiroyoshi
, p. 87 - 102 (2007/10/02)
2'-Azido-2',3'-dideoxyadenosine (9) has been synthesized from adenosine (1) in 6-8 steps.The key intermediate, N6,O5'-bis(4,4'-dimethoxytrityl)-9-(3-deoxy-β-D-threo-pentofuranosyl)adenine (6a), was prepared in a one-flask manner by t