124067-32-9Relevant articles and documents
&γ-AMINO &α-ACETYLENIC EPOXIDES. Preparation and biological activity due to an aldehyde reductase inhibition
Bernard, Didier,Doutheau, Alain,Gore, Jacques,Moulinoux, Jacques,Quemener, Veronique,et al.
, p. 1429 - 1440 (1989)
The preparation of several of the entitled epoxides 3 is described in two steps starting from 2-methyl 2-amino but 3-yne, the first one being the reaction of the lithium acetylide with a α-chloroaldehyde or ketone.In certain cases, this reaction is highly