124083-30-3Relevant academic research and scientific papers
Nitrodienic-like Reactivity of 2-Nitrofuran with Organometallic Reagents: One-step Synthesis of Alkylfuranones
Pecunioso, Angelo,Galoppini, Elena,Menicagli, Rita
, p. 7497 - 7508 (2007/10/02)
2-Nitrofuran reacts with Grignard, alkyllithium, dialkylcadmium and heterocuprate reagents affording mixtures of 5-alkyl- and 3-alkyl-2-furanones.
Synthesis of cis and trans Whisky and Cognac Lactones by the Regiocontrolled Alkylation of 2-(Trimethylsiloxy)furan
Jefford, Charles W.,Sledeski, Adam W.,Boukouvalas, John
, p. 1362 - 1370 (2007/10/02)
The racemic cis- and trans-5-butyltetrahydro-4-methylfuran-2-ones ( = whisky lactones) and their higher homologues tetrahydro-4-methyl-5-pentylfuran-2-ones ( = cognac lactones) have been prepared in 2-3 steps from 2(trimethylsiloxy)furan.Regioselective alkylation of the latter afforded the 5-butyl- and 5-pentylfuran-2(5H)-ones which served as precursors for the stereocontrolled construction of either diastereoisomer of the beverage lactones.The structure and tautomerization of the diazomethane adducts of these 5-alkylfuran-2(5H)-ones are also described.
ALKYLFURANONES FROM 2-NITROFURAN: A PROMISING SYNTHETIC APPROACH
Menicagli, Rita,Pecunioso, Angelo,Galoppini, Elena
, p. 141 - 142 (2007/10/02)
Mixtures of 5- and 3-alkyl-2-furanones are obtained from 2-nitrofuran and Grignard reagents.
