609-39-2 Usage
Description
2-Nitrofuran is a chemical compound that belongs to the nitrofuran class. It is characterized by the presence of a nitro group (-NO2) attached to a furan ring. Nitrofurans are known for their broad-spectrum antimicrobial properties.
Uses
Used in Veterinary Medicine:
2-Nitrofuran is used as a minor antimicrobial agent in veterinary medicine. It is employed to treat bacterial infections in animals, particularly those caused by gram-negative bacteria.
Used in Water Treatment:
Nitrofurans, including 2-nitrofuran, have been used as broad-spectrum antibacterial compounds in water treatment processes. They are added to water to destroy bacteria, ensuring the safety and cleanliness of the water supply.
However, it is important to note that the use of nitrofurans, including 2-nitrofuran, has been withdrawn in the United States by the US Food and Drug Administration (FDA) due to concerns over their safety and potential health risks.
Environmental Fate
2-Nitrofuran is a yellow crystalline solid with molecular weight
of 113.07152 g mol-1. The boiling point of 2-nitrofuran is
84 ℃ at 17 hPa and the melting point is 29–33 ℃. It is
a flammable solid. Its flash point is 88 ℃ (closed cup). Vapor
pressure is 0.398mmHg at 25 ℃. This compound is soluble in
H2O and ethanol. Its density is 1.344 g cm-3.
The partition behavior of 2-nitrofuran in water, sediment,
and soil is 0.8. No data are available on its environmental
persistency (degradation/speciation), long-range transport,
bioaccumulation, and biomagnification. This chemical is
stable but it is incompatible with strong oxidizing agents.
Toxicity evaluation
2-Nitrofuran reacts with DNA to form complexes, induces
interstrand cross-links, produces alkali-labile lesions, and
interferes with nucleic acid synthesis. Removal of the nitro
group decreases the mutagenic activity.
Check Digit Verification of cas no
The CAS Registry Mumber 609-39-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,0 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 609-39:
(5*6)+(4*0)+(3*9)+(2*3)+(1*9)=72
72 % 10 = 2
So 609-39-2 is a valid CAS Registry Number.
InChI:InChI=1S/C4H3NO3/c6-5(7)4-2-1-3-8-4/h1-3H
609-39-2Relevant articles and documents
Reactions of trialkyl(2-furyl)germanes with electrophilic reagents
Lukevics, E.,Ignatovich, L.,Goldberg, Yu.,Polyak, F.,Gaukhman, A.,et al.
, p. 11 - 24 (2007/10/02)
The metallation (n-BuLi), alkylation (t-BuOH/H+), nitration (NO2+ BF4-), bromination (NBS, dioxane dibromide (DDB)), acylation and chlorination (chloramine T) reactions of (2-furyl)germanes were studied.Except for alkylation and bromination with DDB, the reactions involved electrophilic substitution of hydrogen atoms in position 5 or 3 of the furan ring.The alkylation reaction and bromination with DDB occur via ipso-substitution of the trialkylgermyl group.Dichlorocarbene generated by phase-transfer catalysis adds to the 2-germyl-substituted furan at the C4=C5 bond in the ring.Some of the above reactions were conducted with trimethyl(2-furyl)silane and 2-(t-butyl)furan, the silicon and carbon analogues of furylgermanes.The reactivities of the title compounds were compared.