124097-10-5

Upstream product

• 124022-34-0 (+)-(1R,5S)-3-benzyl-5-formyl-1-<((methoxymethyl)oxy)methyl>-9-methylene-3-azabicyclo<3.3.1>nonane 
• 124097-12-7 (+)-(1R,5R)-3-benzyl-1-(hydroxymethyl)-5-methyl-9-methylene-3-azabicyclo<3.3.1>nonane 
• 107-30-2 chloromethyl methyl ether 
• 128466-29-5 (1R,5S,9R)-3-Benzyl-1-hydroxymethyl-5-methyl-3-aza-bicyclo[3.3.1]nonan-9-ol 
• 128466-23-9 (1R,5S,9S)-3-Benzyl-1,5-bis-hydroxymethyl-3-aza-bicyclo[3.3.1]nonan-9-ol 
• 113161-31-2 3-benzyl-1,5-(dihydroxymethyl)-9-methylene-3-azabicyclo<3.3.1>nonane 
• 128466-30-8 (1R,5S,9R)-3-Benzyl-1-methoxymethoxymethyl-5-methyl-3-aza-bicyclo[3.3.1]nonan-9-ol 
• 128466-28-4 C₂₇H₄₁NO₂ 
• 113161-22-1 dimethyl 3-benzyl-9-methylene-3-azabicyclo<3.3.1>nonane-1,5-dicarboxylate 
• 128466-27-3 C₂₇H₃₉NO₃ 
• 124097-11-6 (+)-(1R,5S)-1-(acetoxymethyl)-3-benzyl-5-formyl-9-methylene-3-azabicyclo<3.3.1>nonane 
• 124097-07-0 (-)-(1R,5S)-1-(acetoxymethyl)-3-benzyl-5-hydroxymethyl-9-methylene-3-azabicyclo<3.3.1>nonane 
• 128466-25-1 C₂₇H₄₁NO₃ 
• 128466-25-1 C₂₇H₄₁NO₃ 

Downstream Products

• 124097-12-7 (+)-(1R,5R)-3-benzyl-1-(hydroxymethyl)-5-methyl-9-methylene-3-azabicyclo<3.3.1>nonane 
• 124097-13-8 (+)-(1R,5R,9R)-3-benzyl-9-(hydroxymethyl)-1-<((methoxymethyl)oxy)methyl>-5-methyl-3-azabicyclo<3.3.1>nonane 
• 124097-14-9 (-)-(1R,5R,9S)-3-benzyl-9-(hydroxymethyl)-1-<((methoxymethyl)oxy)methyl>-5-methyl-3-azabicyclo<3.3.1>nonane 
• 124150-10-3 (E)-(-)-(1R,5R,9R)-3-(methoxycarbonyl)-1-<((methoxymethyl)oxy)methyl>-9-(2-methoxystyryl)-5-methyl-3-azabicyclo<3.3.1>nonane 
• 124097-18-3 (-)-(1S,5R,9R)-1-(2-(methoxycarbonyl)ethenyl)-3-(methoxycarbonyl)-5-methyl-9-<2'-<1''-(2''-oxo)cyclohex-3''-enyl>ethyl>-3-azabicyclo<3.3.1>nonane 
• 124022-38-4 (1R,5R,9R)-1-((E)-2-Methoxycarbonyl-vinyl)-5-methyl-9-[2-(6-oxo-cyclohex-1-enyl)-ethyl]-3-aza-bicyclo[3.3.1]nonane-3-carboxylic acid methyl ester 
• 124022-42-0 (1R,5R,9R)-1-Formyl-5-methyl-9-[2-(2-oxo-cyclohex-3-enyl)-ethyl]-3-aza-bicyclo[3.3.1]nonane-3-carboxylic acid methyl ester 
• 124022-36-2 (E)-(-)-(1R,5R,9R)-1-(hydroxymethyl)-3-(methoxycarbonyl)-9-(2-methoxystyryl)-5-methyl-3-azabicyclo<3.3.1>nonane 
• 124022-43-1 (1R,5R,9R)-1-Formyl-5-methyl-9-[2-(6-oxo-cyclohex-1-enyl)-ethyl]-3-aza-bicyclo[3.3.1]nonane-3-carboxylic acid methyl ester 
• 124097-17-2 (1R,5R,9R)-1-Hydroxymethyl-5-methyl-9-[2-(2-oxo-cyclohex-3-enyl)-ethyl]-3-aza-bicyclo[3.3.1]nonane-3-carboxylic acid methyl ester 
• 124022-37-3 (1R,5R,9R)-1-Hydroxymethyl-5-methyl-9-[2-(6-oxo-cyclohex-1-enyl)-ethyl]-3-aza-bicyclo[3.3.1]nonane-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

CHIRAL SYNTHESIS OF THE INTERMEDIATE OF ATISINE

The chiral key intermediate, (+)-(1R,5R)-3-benzyl-1-methoxymethyloxymethyl-5-methyl-9-methylene-3-azabicyclononane (2), for the synthesis of atisine (5) was prepared from dimethyl 3-benzyl-3-azabicyclononan-9-one-1,5-dicarboxylate (6) by a c

Asymmetric total synthesis of atisine via intramolecular double Michael reaction

The bridged, pentacyclic intermediate 2 for atisine (1) was synthesized in a naturally occurring enantiomeric form from dimethyl cyclohexanone-2,6-dicarboxylate (6). The synthesis is composed of the following key steps: (1) formation of the azabicyclo[3.3