124097-17-2

Upstream product

• 124097-12-7 (+)-(1R,5R)-3-benzyl-1-(hydroxymethyl)-5-methyl-9-methylene-3-azabicyclo<3.3.1>nonane 
• 113161-21-0 dimethyl 3-benzyl-3-azabicyclo<3.3.1>nonan-9-one-1,5-dicarboxylate 
• 124097-10-5 (+)-(1R,5R)-3-benzyl-1-<((methoxymethyl)oxy)methyl>-5-methyl-9-methylene-3-azabicyclo<3.3.1>nonane 
• 124097-13-8 (+)-(1R,5R,9R)-3-benzyl-9-(hydroxymethyl)-1-<((methoxymethyl)oxy)methyl>-5-methyl-3-azabicyclo<3.3.1>nonane 
• 124022-28-2 1,5-(diacetoxymethyl)-3-benzyl-9-methylene-3-azabicyclo<3.3.1>nonane 
• 113161-22-1 dimethyl 3-benzyl-9-methylene-3-azabicyclo<3.3.1>nonane-1,5-dicarboxylate 
• 113161-31-2 3-benzyl-1,5-(dihydroxymethyl)-9-methylene-3-azabicyclo<3.3.1>nonane 
• 124022-36-2 (E)-(-)-(1R,5R,9R)-1-(hydroxymethyl)-3-(methoxycarbonyl)-9-(2-methoxystyryl)-5-methyl-3-azabicyclo<3.3.1>nonane 
• 124097-07-0 (-)-(1R,5S)-1-(acetoxymethyl)-3-benzyl-5-hydroxymethyl-9-methylene-3-azabicyclo<3.3.1>nonane 
• 124097-11-6 (+)-(1R,5S)-1-(acetoxymethyl)-3-benzyl-5-formyl-9-methylene-3-azabicyclo<3.3.1>nonane 
• 124150-10-3 (E)-(-)-(1R,5R,9R)-3-(methoxycarbonyl)-1-<((methoxymethyl)oxy)methyl>-9-(2-methoxystyryl)-5-methyl-3-azabicyclo<3.3.1>nonane 
• 124022-34-0 (+)-(1R,5S)-3-benzyl-5-formyl-1-<((methoxymethyl)oxy)methyl>-9-methylene-3-azabicyclo<3.3.1>nonane 
• 124097-16-1 (-)-(1R,5R,9R)-9-formyl-3-(methoxycarbonyl)-1-<((methoxymethyl)oxy)methyl>-5-methyl-3-azabicyclo<3.3.1>nonane 
• 124097-15-0 (-)-(1R,5R,9R)-9-(hydroxymethyl)-3-(methoxycarbonyl)-1-<((methoxymethyl)oxy)methyl>-5-methyl-3-azabicyclo<3.3.1>nonane 

Relevant academic research and scientific papers

Asymmetric total synthesis of atisine via intramolecular double Michael reaction

The bridged, pentacyclic intermediate 2 for atisine (1) was synthesized in a naturally occurring enantiomeric form from dimethyl cyclohexanone-2,6-dicarboxylate (6). The synthesis is composed of the following key steps: (1) formation of the azabicyclo[3.3