6266-89-3

Usage

Molecular structure

2,6-bis[2-(4-methoxyphenyl)ethenyl]pyridine is composed of a pyridine ring with two ethenyl groups, each containing a 4-methoxyphenyl substituent.

Chemical family

It is a member of the stilbene family.

Properties

Stilbenes are known for their fluorescence and potential biological activities.

Uses

It is often used as a fluorescent probe in biological applications.

Potential

Its potential medicinal properties make it a subject of interest for drug development.

Versatility

The compound has various potential applications in physics, chemistry, and biology.

Upstream product

• 108-48-5 2,6-dimethylpyridine 
• 123-11-5 4-methoxy-benzaldehyde 
• 15485-22-0 4-chloro-N-[(4-methoxyphenyl)methylidene]aniline 
• 61973-87-3 tetraethyl 2,6-bis(methanephosphonate)pyridine 

Downstream Products

• 7596-85-2 2,6-bis-(4-methoxy-trans-styryl)-1-methyl-pyridinium; toluene-4-sulfonate 
• 1241-14-1 2,6-bis[2-(4-hydroxyphenyl)ethenyl]pyridine 
• 47550-86-7 2r,6c-bis-(4-methoxy-phenethyl)-1-methyl-piperidine 
• 818377-33-2 (2S,6R)-2,6-Bis-[2-(4-methoxy-phenyl)-ethyl]-piperidine 

Relevant academic research and scientific papers

Solvatochromism of symmetrical 2,6-distyrylpyridines. An experimental and theoretical study

Seven symmetrical 2,6-distyrylpyridines, phenyl-substituted with hydrogen-bond donors, hydrogen-bond acceptors, halogens and hydrophobic moieties were synthesized and their spectroscopic characterization was done. Solvent effects on the absorption and fluorescence spectra were analyzed and quantified using the Kamlet-Taft and Catalán approach. The obtained results were rationalized by comparison of electrostatic potentials of the molecules in the ground and in excited state and by comparison of the frontier molecular orbitals (HOMO and LUMO), derived from quantum-mechanical calculations (HF, DFT, MP2). Analysis of the results revealed an important influence of non-specific (dispersive) interactions on the solvatochromic behavior of the compounds. 1D and 2D NMR data, in silico obtained conformational assembly of the compound, and the NMR analysis of molecular flexibility in solution (NAMFIS), were used to estimate population of conformers and to deconvolute the UV-Vis spectrum of representative derivative; inferring that the conformational assembly is more complex than was assumed in so far published literature data for this class of compounds. Along with this, the emission spectra of the representative compounds were decomposed by the Multivariate Curve Resolution analysis.

Polymers and oligomers, their synthesis, and electronic devices incorporating same

The invention relates to polymers and oligomers, methods of their synthesis, and electronic devices comprising them.

Lobelane analogues as novel ligands for the vesicular monoamine transporter-2

A series of lobelane analogues has been synthesized and their structure-activity relationships at the vesicular monoamine transporter-2 (VMAT2) have been evaluated. The most potent analogues in this series were the cis-2,6-piperidino analogues, 25b, 27b, 28b, and 30b, with Ki values ranging from 430 to 580 nM.

Anil-Synthese. 22 Mitteilung. Ueber die Herstellung von Styryl und Distyryl-Derivaten des Pyridins

2,4-, 2,5- and 2,6-Dimethylpyridines react with anils of aromatic aldehydes in the presence of dimethylformamide and potassium hydroxide to yield the corresponding distyrylpyridines ('anil synthesis').Under the same reaction conditions (4-methylstyryl)pyridines are converted to (stilbenylvinyl)pyridines.Similarly, the Schiff's base derived from pyridine-3-carbaldehyde and chloranile on treatment with methyl- and p-tolyl-substituted aromatic hetericycles gives the corresponding (heteroaryl-styryl)pyridines, whereas with the Schiff's bases derived from pyridine-2= and -4-carbaldehyde side reactions, such as dimerization followed by disproportionation predominate.