1241052-08-3Relevant academic research and scientific papers
Systematic investigations on the reduction of 4-aryl-4-oxoesters to 1-aryl-1,4-butanediols with methanolic sodium borohydride
Chaudhuri, Subrata Kumar,Saha, Manabendra,Saha, Amit,Bhar, Sanjay
supporting information; experimental part, p. 748 - 755 (2011/01/03)
4-Aryl-4-oxoesters undergo facile reduction of both the keto and the ester groups with methanolic NaBH4 at room temperature to yield the corresponding 1-aryl-1,4-butanediols whereas 4-alkyl-4-oxoesters furnish the corresponding 1,4-butanolides via selective reduction of the keto moiety. Results of a detailed and systematic investigation of the reaction are described.
