1241680-48-7

Basic information

• Product Name: 4-Phosphono-D-Phenylalanine
• Synonyms: 4-Phosphono-D-Phenylalanine;D-4-Phosphono-Phe-OH
• CAS NO: 1241680-48-7
• Molecular Formula: C9H12NO5P
• Molecular Weight: 245.169041
• Mol File: 1241680-48-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Phosphono-D-Phenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Phosphono-D-Phenylalanine(1241680-48-7)
• EPA Substance Registry System: 4-Phosphono-D-Phenylalanine(1241680-48-7)

Safety Data

• Hazardous Substances Data: 1241680-48-7(Hazardous Substances Data)

Upstream product

• 103882-09-3 N-Boc-4-I-Phe-OH 
• 943148-40-1 (S)-2-tert-butoxycarbonylamino-3-(4-iodo-phenyl)-propionic acid ethyl ester 
• 943148-41-2 (S)-2-tert-butoxycarbonylamino-3-[4-(diethoxy-phosphoryl)-phenyl]-propionic acid ethyl ester 
• 132067-41-5 methyl (±)-3-(4-bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoate 
• 14091-15-7 p-bromo-DL-phenylalanine 
• 132153-48-1 N-(tert-Butyloxycarbonyl)-4-bromo-DL-phenylalanine 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 71078-92-7 diethyl (acetylamino)<(4-bromophenyl)methyl>propanedioate 
• 120667-47-2 diethyl (acetylamino)<<4-(diethoxyphosphinyl)phenyl>methyl>propanedioate 
• 132067-42-6 N-(tert-Butyloxycarbonyl)-4-(diethoxyphosphono)-DL-phenylalanine methyl ester 

Relevant articles and documents

Efficient synthesis of protected l-phosphonophenylalanine (Ppa) derivatives suitable for solid phase peptide synthesis

l-Phosphonophenylalanine (Ppa) derivatives were synthesized from l-4-iodophenylalanine and suitably protected phosphites using Michaelis-Arbuzov reaction conditions in the presence of Pd(0) and triethylamine at 70 ± 2 °C.

Exploration of phenyl-spaced 2-amino-(5-9)-phosphonoalkanoic acids as competitive N-methyl-D-aspartic acid antagonists

To investigate the preferred spatial relationship of the distal phosphonic acid to the α-amino acid group of the established competitive N-methyl-D-aspartic acid (NMDA) antagonists APH (1) and APV (2), we have prepared a series of ortho-, meta-, and para-