1241777-72-9

Upstream product

• 131653-79-7 2-(5'-bromo-3'-indolyl)-1-nitroethene 
• 877-03-2 5-bromo-1H-indole-3-carboxaldehyde 
• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 
• 77128-73-5 (2S)-N-fluorenylmethyloxycarbonyl-2-amino-N-methyl-3-phenylpropanoic acid 
• 1241777-71-8 C₃₅H₃₂BrN₃O₃ 

Downstream Products

• 1241777-73-0 C₃₆H₃₄BrN₃O₂ 
• 125443-66-5 eudistomidin B 
• 1384331-20-7 C₃₅H₃₂BrN₃O₂ 
• 1318767-45-1 eudistomidin I 

Relevant academic research and scientific papers

Enantioselective total synthesis of eudistomidins G, H, and I

Asymmetric first total synthesis of eudistomidins G, H, and I, tetrahydro-β-carboline alkaloids from the Okinawan marine tunicate Eudistoma glaucus, has been accomplished with the Bischler-Napieralski reaction and the Noyori catalytic asymmetric hydrogen-transfer reaction. The absolute configurations of eudistomidins G, H, and I were confirmed from comparison of the 1H and 13C NMR, and CD spectral data of synthetic and natural eudistomidins G, H, and I, respectively.

Eudistomidin G, a new β-carboline alkaloid from the Okinawan marine tunicate Eudistoma glaucus and structure revision of eudistomidin B

A new β-carboline alkaloid, eudistomidin G (1), has been isolated from the Okinawan marine tunicate Eudistoma glaucus, and the structure was elucidated from spectroscopic data. Furthermore, the structure of eudistomidin B (2), which has been isolated from the same tunicate, was revised from 2a to 2b by detailed analyses of spectroscopic data. Asymmetric synthesis of the revised structure (2b) of eudistomidin B (2) and its (1S,10S)-diastereomer (2c) has been accomplished with the Noyori catalytic asymmetric hydrogen-transfer reaction. The absolute configuration of eudistomidin B (2) was confirmed to be 2b possessing (1R,10S)-configuration, from comparison of the 1H NMR data, CD spectra, [α]D values, and HPLC analysis of 2b, 2c, and natural eudistomidin B.