1241914-79-3Relevant academic research and scientific papers
(Het)aryl Difluoromethyl-Substituted β-Alkoxyenones: Synthesis and Heterocyclizations
Bugera, Maksym Ya.,Tarasenko, Karen V.,Kondratov, Ivan S.,Gerus, Igor I.,Vashchenko, Bohdan V.,Ivasyshyn, Viktor E.,Grygorenko, Oleksandr O.
, p. 1069 - 1077 (2020)
An efficient approach to the preparation of β-alkoxyenones bearing (het)aryl difluoromethyl substituents is described. The method included acylation of acyclic or cyclic vinyl ethers with (het)aryl difluoroacetyl chlorides. The method worked well for most
ADENOSINE A3 RECEPTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF
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, (2012/03/12)
Provided herein is a method of preventing, treating, or ameliorating one or more symptoms of an adenosine A3-mediated condition, disorder, or disease, with a compound of Formula I. Also provided herein is a method of preventing, treating, or ameliorating one or more symptoms of glaucoma or ocular hypertension. Further provided herein is a method of modulating the activity of an adenosine A3 receptor.
4-AZOLYLAMINOQUINAZOLINE DERIVATIVES AND METHODS OF USE THEREOF
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Page/Page column 83, (2012/03/26)
Provided herein are 4-azolylaminoquinazoline compounds for treatment of JAK kinase mediated diseases, including JAK2 kinase-, JAK3 kinase- or TYK2 kinase-mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.
JAK KINASE MODULATING QUINAZOLINE DERIVATIVES AND METHODS OF USE THEREOF
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Page/Page column 92-93, (2010/09/17)
Provided herein are quinazoline compounds for treatment of JAK kinase mediated diseases, including JAK2 kinase-, JAK3 kinase- or TYK2 kinase-mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions. (I).
