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Sovriad, also known as Simeprevir, is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A) protease, which is essential for HCV replication. It effectively inhibits HCV viral replication and is particularly effective against HCV genotypes 1a and 1b.

1241946-89-3

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1241946-89-3 Usage

Uses

Used in Pharmaceutical Industry:
Sovriad is used as an antiviral agent for the treatment of hepatitis C virus (HCV) infections. It works by inhibiting the NS3/4A protease, which is crucial for the replication of the virus. Sovriad has demonstrated effectiveness against HCV genotypes 1a and 1b and can be used alone or in combination with other antiviral medications such as pegylated IFN-α and ribavirin.
Additionally, Sovriad has shown synergistic effects when used in combination with IFN-α or NM-107, and an additive effect when used with ribavirin, enhancing the overall treatment efficacy for patients with hepatitis C.

Check Digit Verification of cas no

The CAS Registry Mumber 1241946-89-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,1,9,4 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1241946-89:
(9*1)+(8*2)+(7*4)+(6*1)+(5*9)+(4*4)+(3*6)+(2*8)+(1*9)=163
163 % 10 = 3
So 1241946-89-3 is a valid CAS Registry Number.

1241946-89-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name TMC 435 sodium salt

1.2 Other means of identification

Product number -
Other names Simeprevir sodium

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1241946-89-3 SDS

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