1241952-06-6Relevant academic research and scientific papers
Enantioselective synthesis of (1E, 3S)-1-iodoundec-1-en-5-yn-3-ol, the eicosanoid synthon
Lapitskaya,Vasiljeva,Pivnitsky
, p. 1067 - 1071 (2009)
A synthesis of the title compound, the synthon for the constanolactones and other eicosanoids, has been developed from achiral starting compounds. The synthesis is based on the S-enantiodirected dihydroxylation of the double bond to introduce a chirality and on the use of conformational restriction of the triple bond (the latent Z-double bond) surroundings.
