1241958-35-9Relevant academic research and scientific papers
Synthesis and anti-microbial activity of some new fluorinated 1H-pyrazoles
Wang, Dun-Jia,Fan, Ling,Zheng, Chun-Yang,Fang, Zheng-Dong
, p. 584 - 586 (2010)
Several new trifluoromethyl-1H-pyrazoles were prepared by reaction of hydrazine monohydrate with 1,3-diketones. Their structures were confirmed by elemental analysis, IR, 1H NMR and EI-MS spectroscopy. The anti-microbial activities of the newly synthesized compounds were examined by disc diffusion method against Escherichia coli, Staphylococcus aureus, Pyricularia oryzae and Rhizoctnia solani. All the trifluoromethyl-1H-pyrazoles exhibited a certain degree of anti-bacterial and anti-fungal activities.
