190020-14-5

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 15 carbon (C) atoms, 13 hydrogen (H) atoms, 3 fluorine (F) atoms, and 3 oxygen (O) atoms.

Explanation

The structure describes the arrangement of atoms and functional groups in the molecule. It features a benzyl group attached to the oxygen atom of a phenolic function, and a trifluorobutane-1,3-dione backbone.

Explanation

A chemical compound is a substance formed when two or more chemical elements are chemically bonded together in a fixed proportion.

Explanation

The compound is a derivative of trifluorobutane-1,3-dione, which means it is structurally related to the parent compound but has additional functional groups or modifications.

Explanation

The compound is used as a building block for the synthesis of various organic molecules, particularly in the fields of organic chemistry and pharmaceutical research.

Explanation

The compound is a solid at room temperature, and it has a yellow color.

Explanation

The compound has limited solubility in water but dissolves well in organic solvents such as diethyl ether and acetone.

Explanation

Due to potential hazards associated with the compound, it is essential to handle it carefully and follow appropriate safety measures to minimize risks.

Structure

1-(4-benzyloxyphenyl)-4,4,4-trifluorobutane-1,3-dione

Type

Chemical compound

Derivative

Trifluorobutane-1,3-dione

Application

Organic synthesis and pharmaceutical research

Physical State

Yellow solid

Solubility

Sparingly soluble in water, soluble in organic solvents

Safety Precautions

Handle with caution, follow proper safety protocols

Upstream product

• 383-63-1 ethyl trifluoroacetate, 
• 54696-05-8 4'-benzyloxy-acetophenone 

Downstream Products

• 1241958-35-9 5-(4-(benzyloxy)phenyl)-3-(trifluoromethyl)-1H-pyrazole 

Relevant academic research and scientific papers

1,5-Diketones Synthesis via Three-Component Cascade Reaction

A mild and efficient cascade synthesis of 1,5-diketones from readily available N,N-dicyclohexylmethylamine, 1,3-dicarbonyl compounds, and trifluoromethyl β-diketones has been developed. This cascade reaction occurs via an oxidation/Mannich reaction/Cope elimination/Michael addition/retro-Claisen reaction sequence, and provides multiple C-C bond formations in one pot. In addition, exquisite chemoselectivity is achieved in the reaction between 1,3-dicarbonyl compounds and trifluoromethyl β-diketones.

Synthesis and anti-microbial activity of some new fluorinated 1H-pyrazoles

Several new trifluoromethyl-1H-pyrazoles were prepared by reaction of hydrazine monohydrate with 1,3-diketones. Their structures were confirmed by elemental analysis, IR, 1H NMR and EI-MS spectroscopy. The anti-microbial activities of the newly synthesized compounds were examined by disc diffusion method against Escherichia coli, Staphylococcus aureus, Pyricularia oryzae and Rhizoctnia solani. All the trifluoromethyl-1H-pyrazoles exhibited a certain degree of anti-bacterial and anti-fungal activities.

Substituted isoxazolines, pharmaceutical compositions containing the same, methods of preparing the same, and uses of the same

The invention relates to substituted isoxazolines according to the general formula (I) : in which A, R1, R2, R3, R4, Z, X, m, n, and p, are given in the claims, and salts thereof, to pharmaceutical compositions comprising said substituted isoxazolines, to methods of preparing said substituted isoxazolines as well as the use thereof for manufacturing a pharmaceutical composition for the treatment of diseases known to be at least in part mediated by HDAC activity or whose symptoms are known to be alleviated by HDAC inhibitors.

Three hybrid assay system

The invention provides compositions and methods for isolating ligand binding polypeptides for a user-specified ligand, and for isolating small molecule ligands for a user-specified target polypeptide using an improved class of hybrid ligand compounds.

Method of detecting cyclooxygenase-2

The invention relates to a method of detecting concentrations of cyclooxygenase-2 in a mammal, the method comprising: administering to the mammal a diagnostically effective amount of a cyclooxygenase-2 selective agent, which is capable of being detected in vivo; and b) detecting the agent so the concentration of cyclooxygenase-2 is detected.