1241973-04-5

Basic information

• Product Name: (1R,2R)-(+)-2-[4-(3,4-dimethylphenyl)piperazin-1-yl]-1,2-dihydronaphthalen-1-ol
• Synonyms: (1R,2R)-(+)-2-[4-(3,4-dimethylphenyl)piperazin-1-yl]-1,2-dihydronaphthalen-1-ol
• CAS NO: 1241973-04-5
• Molecular Weight: 334.461
• Mol File: 1241973-04-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1R,2R)-(+)-2-[4-(3,4-dimethylphenyl)piperazin-1-yl]-1,2-dihydronaphthalen-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R)-(+)-2-[4-(3,4-dimethylphenyl)piperazin-1-yl]-1,2-dihydronaphthalen-1-ol(1241973-04-5)
• EPA Substance Registry System: (1R,2R)-(+)-2-[4-(3,4-dimethylphenyl)piperazin-1-yl]-1,2-dihydronaphthalen-1-ol(1241973-04-5)

Safety Data

• Hazardous Substances Data: 1241973-04-5(Hazardous Substances Data)

Upstream product

• 573-57-9 1,4-dihydronaphthalene-1,4-epoxide 
• 1014-05-7 1-(3,4-dimethylphenyl)piperazine 
• 573-57-9 1,4-epoxy-1,4-dihydronaphthalene 
• 118-92-3 anthranilic acid 

Relevant articles and documents

Iridium-catalyzed asymmetric ring-opening of oxabenzonorbornadienes with N-substituted piperazine nucleophiles

Iridium-catalyzed asymmetric ring-opening of oxabenzonorbornadienes with N-substituted piperazines was described. The reaction afforded the corresponding ring-opening products in high yields and moderate enantioselectivities in the presence of 2.5 mol % [Ir(COD)Cl]2 and 5.0 mol % (S)-p-Tol-BINAP. The effects of various chiral bidentate ligands, catalyst loading, solvent, and temperature on the yield and enantioselectivity were also investigated. A plausible mechanism was proposed to account for the formation of the corresponding trans-ring opened products based on the X-ray structure of product 2i.