1242046-89-4Relevant academic research and scientific papers
Efficient synthesis of 1-arylquinoxalin-2(1H)-ones via cyclocondensation of N-Aryl-substituted 2-nitrosoanilines with functionalized alkyl acetates
Wrobel, Zbigniew,Stachowska, Karolina,Kwast, Andrzej,Goscik, Agata,Krolikiewicz, Magdalena,Pawlowski, Robert,Turska, Izabela
, p. 956 - 968 (2013/06/27)
N-Aryl-substituted 2-nitrosoanilines (=2-nitrosobenzenamines) 1, readily available by nucleophilic substitution of the ortho-H-atom in nitroarenes with arenamines, react with 2-substituted acetic acid esters in the presence of a weak base giving 1-arylquinoxalin-2(1H)-ones (Scheme 2). This cyclocondensation allows for the synthesis of compounds 2-4, unsubstituted at C(3) or substituted by alkyl, aryl, ester, amide, and keto groups, in good to excellent yields (Tables 1-4). Copyright
An efficient domino synthesis of quinoxalin-2(1H)-ones via an S NAr/coupling/demesylation reaction catalyzed by copper(I) as key step
Chen, Dingben,Bao, Weiliang
supporting information; experimental part, p. 955 - 960 (2010/06/15)
An efficient copper-catalyzed method for the synthesis of quinoxalin-2(1H)-ones derivatives via domino SNAr/coupling/ demesylation reaction of N-(2-halophenyl)methylsulfonamides with 2-halo amides has been developed. Various quinoxalinones with
