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1242052-82-9

2-amino-4-(3-chlorophenylamino)-6-methoxy-5-nitrosopyrimidine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1242052-82-9 Structure

  • Basic information

    1. Product Name: 2-amino-4-(3-chlorophenylamino)-6-methoxy-5-nitrosopyrimidine
    2. Synonyms: 2-amino-4-(3-chlorophenylamino)-6-methoxy-5-nitrosopyrimidine
    3. CAS NO:1242052-82-9
    4. Molecular Formula:
    5. Molecular Weight: 279.686
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1242052-82-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-amino-4-(3-chlorophenylamino)-6-methoxy-5-nitrosopyrimidine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-amino-4-(3-chlorophenylamino)-6-methoxy-5-nitrosopyrimidine(1242052-82-9)
    11. EPA Substance Registry System: 2-amino-4-(3-chlorophenylamino)-6-methoxy-5-nitrosopyrimidine(1242052-82-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1242052-82-9(Hazardous Substances Data)

1242052-82-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1242052-82-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,2,0,5 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1242052-82:
(9*1)+(8*2)+(7*4)+(6*2)+(5*0)+(4*5)+(3*2)+(2*8)+(1*2)=109
109 % 10 = 9
So 1242052-82-9 is a valid CAS Registry Number.

1242052-82-9Relevant articles and documents

A new series of antibacterial nitrosopyrimidines: Synthesis and structure-activity relationship

Olivella, Monica,Marchal, Antonio,Nogueras, Manuel,Melguizo, Manuel,Lima, Beatriz,Tapia, Alejandro,Feresin, Gabriela E.,Parravicini, Oscar,Giannini, Fernando,Andujar, Sebastin A.,Cobo, Justo,Enriz, Ricardo D.

, p. 68 - 80 (2015/01/30)

New nitrosopyrimidines were synthesized and evaluated as potential antibacterial agents. Different compounds structurally related with 4,6-bis(alkyl or arylamino)-5-nitrosopyrimidines were evaluated. Some of these nitrosopyrimidines displayed significant antibacterial activity against human pathogenic bacteria. Among them compounds 1c, 2a-c, and 9a-c exhibited remarkable activity against methicillin-sensitive and -resistant Staphylococcus aureus, Escherichia coli, Yersinia enterocolitica, and Salmonella enteritidis. A detailed structure-activity relationship study, supported by theoretical calculations, aided us to identify and understand the minimal structural requirements for the antibacterial action of the nitrosopyrimidines reported here. Thus, our results have led us to identify a topographical template that provides a guide for the design of new nitrosopyrimidines with antibacterial effects.

Structure-activity relationship study of nitrosopyrimidines acting as antifungal agents

Olivella, Monica,Marchal, Antonio,Nogueras, Manuel,Sanchez, Adolfo,Melguizo, Manuel,Raimondi, Marcela,Zacchino, Susana,Giannini, Fernando,Cobo, Justo,Enriz, Ricardo D.

, p. 6109 - 6122 (2012/11/07)

The design, synthesis, in vitro evaluation, and conformational study of nitrosopyrimidine derivatives acting as antifungal agents are reported. Different compounds structurally related with 4,6-bis(alkyl or arylamino)-5-nitrosopyrimidines were evaluated. Some of these nitrosopyrimidines have displayed a significant antifungal activity against human pathogenic strains. In this paper, we report a new group of nitrosopyrimidines acting as antifungal agents. Among them, compounds 2a, 2b and 15, the latter obtained from a molecular modeling study, exhibited antifungal activity against Candida albicans, Candida tropicalis and Cryptococcus neoformans. We have performed a conformational and electronic analysis on these compounds by using quantum mechanics calculations in conjunction with Molecular Electrostatic Potentials (MEP) obtained from B3LYP/6-31G(d) calculations. Our experimental and theoretical results have led us to identify a topographical template which may provide a guide for the design of new nitrosopyrimidines with antifungal effects.

Alkoxy-5-nitrosopyrimidines: Useful building block for the generation of biologically active compounds

Marchal, Antonio,Nogueras, Manuel,Sanchez, Adolfo,Low, John N.,Naesens, Lieve,De Clercq, Erik,Melguizo, Manuel

supporting information; experimental part, p. 3823 - 3830 (2010/10/04)

Several alkoxy-5-nitrosopyrimidines were synthesised and high regioselective and sequential nucleophilic aromatic substitution of methoxy groups in 2-am:ino-4,6-d.imetho;xy-5nitrosopyrimidine was observed. The approach was applied to the synthesis of valu

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