1242149-41-2Relevant academic research and scientific papers
Generation of diverse 2 H-isoindol-1-ylphosphonates via three-component reaction of 2-alkynylbenzaldehyde, aniline, and phosphite
Yu, Xingxin,Ding, Qiuping,Wu, Jie
experimental part, p. 743 - 746 (2010/11/03)
Diverse 2H-isoindol-1-ylphosphonates as potential HCT-116 inhibitors are easily generated via a FeCl3 and PdCl2 cocatalyzed three-component reaction of 2-alkynylbenzaldehyde, aniline, and phosphite. The focused small library is constructed based on parallel diversity-oriented synthesis.
