124225-40-7Relevant articles and documents
Synthesis of (E)- and (Z)-bromobis(triphenylphosphine)palladium and the X-ray Crystal Structure Determination for the E-Isomer
Dotson, Garry D.,Kampf, Jeffrey W.,Woodard, Ronald W.
, p. 5774 - 5778 (1994)
We report the preparation of (E)- and (Z)-bromobis(triphenylphosphine)palladium from the corresponding ethyl (E)- and (Z)-3-bromo-2-propenoate and the X-ray crystal structure determination for (E)-bromobis(triphenylphosphine)palladium.The (E)-palladium complex was reduced to (E)-3-phosphoenolpyruvate by treatment with a mixture of trifluoroacetic acid-d/trifluoroacetic anhydride under strict anhydrous conditions.The 1H-NMR spectrum of the E-isomer obtained from the reduction of the palladium complex was identical to the 1H-NMR spectra of (E)-3-phosphoenolpyruvate previously prepared by two different synthetic strategies.The X-ray structure of the palladium phosphoenolpyruvate analogue is the first X-ray structure of any 3-substituted phosphoenolpyruvate analogue reported and along with its synthesis and transformation interrelates the stereochemistry of several 3-substituted phosphoenolpyruvate analogues.
