124244-43-5Relevant academic research and scientific papers
Efficient Formation of 2,3-Dihydrofurans via Iron-Catalyzed Cycloisomerization of α-Allenols
Gudmundsson, Arnar,Gustafson, Karl P. J.,Mai, Binh Khanh,Yang, Bin,Himo, Fahmi,B?ckvall, Jan-E.
, p. 12 - 16 (2018/01/17)
Herein, we report a highly efficient iron-catalyzed intramolecular nucleophilic cyclization of α-allenols to furnish substituted 2,3-dihydrofurans under mild reaction conditions. A highly diastereoselective variant of the reaction was developed as well, g
Enzyme- and Ruthenium-Catalyzed Enantioselective Transformation of α-Allenic Alcohols into 2,3-Dihydrofurans
Yang, Bin,Zhu, Can,Qiu, Youai,B?ckvall, Jan-E.
, p. 5568 - 5572 (2016/05/09)
An efficient one-pot method for the enzyme- and ruthenium-catalyzed enantioselective transformation of α-allenic alcohols into 2,3-dihydrofurans has been developed. The method involves an enzymatic kinetic resolution and a subsequent ruthenium-catalyzed c
SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION
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Page/Page column 48, (2015/01/06)
The present invention relates to catalyst complexes comprising palladium (Pd) and at least one spiro-1,1 '-biindane-7,7'- bisphosphine oxide ligand as disclosed herein, and their use. The present invention is further directed to the asymmetric Pd-catalyzed covalent carbon-carbon single bond formation from aryl, heteroaryl and alkenyl triflates and halides and olefins utilising the said catalyst complexes.
Ruthenium-catalyzed olefin metathesis double-bond isomerization sequence
Schmidt, Bernd
, p. 7672 - 7687 (2007/10/03)
A novel ruthenium-catalyzed tandem ring-closing metathesis (RCM) double-bond isomerization reaction is described in this paper. The utility of this method for the efficient syntheses of five-, six-, and seven-membered cyclic enol ethers is demonstrated. It relies on the conversion of a metathesis-active ruthenium carbene species to an isomerization-active ruthenium-hydride species in situ. This conversion is achieved by using various additives. Scope and limitations of the different protocols are discussed, and some mechanistic considerations based on 31P and 1H NMR spectroscopic studies are presented.
An olefin metathesis/double bond isomerization sequence catalyzed by an in situ generated ruthenium hydride species
Schmidt, Bernd
, p. 816 - 819 (2007/10/03)
The direct conversion of allyl ethers to cyclic enol ethers using an olefin metathesis/double bond migration sequence is described. Ruthenium carbene complexes were activated to catalyze the double bond migration step by addition of hydride sources, such
Palladium-Catalyzed Synthesis of trans-2,5-Diaryltetrahydrofurans, Potent Platelet-Activating Factor Antagonists
Larock, Richard,Gong, William H.
, p. 407 - 408 (2007/10/02)
trans-2,5-Diaryltetrahydrofurans 1-3, potent platelet-activating factor antagonists, have been synthesized regio- and stereoselectively by a three-step approach involving sequential palladium-catalyzed diarylation of 2,3-dihydrofuran and subsequent hydrog
