1242441-48-0 Usage
Uses
Used in Chemical Research:
(1S,2S)-ethyl 2-(4-(5-((5-chloropyridin-2-yl)thio)-1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate is used as a research compound for studying its chemical properties and reactivity. Its unique structure allows chemists to investigate its potential interactions with other molecules and its behavior under various conditions.
Used in Pharmaceutical Development:
In the pharmaceutical industry, (1S,2S)-ethyl 2-(4-(5-((5-chloropyridin-2-yl)thio)-1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate may be utilized as a starting material or intermediate in the synthesis of new drugs. Its diverse functional groups could be exploited to create novel therapeutic agents with specific biological activities.
Used in Biological Studies:
(1S,2S)-ethyl 2-(4-(5-((5-chloropyridin-2-yl)thio)-1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate can be employed as a tool in biological research to probe the interactions between (1S,2S)-ethyl 2-(4-(5-((5-chloropyridin-2-yl)thio)-1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate and various biological targets, such as enzymes, receptors, or other proteins. This could lead to a better understanding of its potential biological effects and applications.
Used in Material Science:
In the field of material science, (1S,2S)-ethyl 2-(4-(5-((5-chloropyridin-2-yl)thio)-1H-imidazol-4-yl)phenyl)cyclopropanecarboxylate might be explored for its potential to contribute to the development of new materials with unique properties, such as polymers, coatings, or sensors, based on its chemical structure and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 1242441-48-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,2,4,4 and 1 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1242441-48:
(9*1)+(8*2)+(7*4)+(6*2)+(5*4)+(4*4)+(3*1)+(2*4)+(1*8)=120
120 % 10 = 0
So 1242441-48-0 is a valid CAS Registry Number.
1242441-48-0Relevant academic research and scientific papers
Discovery of MK-3168: A PET tracer for imaging brain fatty acid amide hydrolase
Liu, Ping,Hamill, Terence G.,Chioda, Marc,Chobanian, Harry,Fung, Selena,Guo, Yan,Chang, Linda,Bakshi, Raman,Hong, Qingmei,Dellureficio, James,Lin, Linus S.,Abbadie, Catherine,Alexander, Jessica,Jin, Hong,Mandala, Suzanne,Shiao, Lin-Lin,Li, Wenping,Sanabria, Sandra,Williams, David,Zeng, Zhizhen,Hajdu, Richard,Jochnowitz, Nina,Rosenbach, Mark,Karanam, Bindhu,Madeira, Maria,Salituro, Gino,Powell, Joyce,Xu, Ling,Terebetski, Jenna L.,Leone, Joseph F.,Miller, Patricia,Cook, Jacquelynn,Holahan, Marie,Joshi, Aniket,O'Malley, Stacey,Purcell, Mona,Posavecz, Diane,Chen, Tsing-Bau,Riffel, Kerry,Williams, Mangay,Hargreaves, Richard,Sullivan, Kathleen A.,Nargund, Ravi P.,DeVita, Robert J.
, p. 509 - 513 (2013/07/26)
We report herein the discovery of a fatty acid amide hydrolase (FAAH) positron emission tomography (PET) tracer. Starting from a pyrazole lead, medicinal chemistry efforts directed toward reducing lipophilicity led to the synthesis of a series of imidazole analogues. Compound 6 was chosen for further profiling due to its appropriate physical chemical properties and excellent FAAH inhibition potency across species. [11C]-6 (MK-3168) exhibited good brain uptake and FAAH-specific signal in rhesus monkeys and is a suitable PET tracer for imaging FAAH in the brain.
IMIDAZOLE DERIVATIVES USEFUL AS MODULATORS OF FAAH AND AS FAAH IMAGING AGENTS
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Page/Page column 47, (2010/09/18)
The present invention is directed to certain Inidazole derivatives which are useful as modulators of Fatty Acid Amide Hydrolase (FAAH) and as FAAH imaging agents. The invention is also concerned with pharmaceutical formulations comprising these compounds
