124252-78-4Relevant academic research and scientific papers
Synthesis and biological activity of bromolignans and cyclolignans
San Feliciano,Medarde,Pelaez Lamamie De Clairac,Lopez,Puebla,Gravalos,Lazaro,De Quesada
, p. 421 - 426 (1993)
Nine lignan derivatives (4-12) have been obtained from (-)-yatein by treatment with DDQ and NBS. They showed moderate antineoplastic activity (P-388, A-549, HT-29) compared with podophyllotoxin, but some of them have a better therapeutic index. None of the tested compounds shows antiviral (HSV-1, VSV) or enzyme inhibitor (ADA, DHFR, GST) activities.
THE STRUCTURE OF YATEIN. DETERMINATION OF THE POSITIONS, AND CONFIGURATIONS OF BENZYL GROUPS IN LIGNANS OF THE 2,3-DIBENZYLBUTYROLACTONE TYPE
Harmatha, Juraj,Budesinsky, Milos,Trka, Antonin
, p. 644 - 663 (2007/10/02)
The structure of yatein isolated from Libocedrus yateensis has been determined as (2R,3R)-2-(3,4,5-trimethoxybenzyl)-3-(3,4-methylenedioxybenzyl)butyrolactone (Ia).The assignment of individual signals of the 1H NMR spectrum of yatein and further lignans o
