Archiv der Pharmazie p. 421 - 426 (1993)
Update date:2022-09-26
Topics:
San Feliciano
Medarde
Pelaez Lamamie De Clairac
Lopez
Puebla
Gravalos
Lazaro
De Quesada
Nine lignan derivatives (4-12) have been obtained from (-)-yatein by treatment with DDQ and NBS. They showed moderate antineoplastic activity (P-388, A-549, HT-29) compared with podophyllotoxin, but some of them have a better therapeutic index. None of the tested compounds shows antiviral (HSV-1, VSV) or enzyme inhibitor (ADA, DHFR, GST) activities.
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Doi:10.1016/j.tetlet.2010.06.125
(2010)Doi:10.1021/jo101547w
(2010)Doi:10.1016/j.ejmech.2010.05.051
(2010)Doi:10.1016/j.tetasy.2010.03.045
(2010)Doi:10.1021/ja106632j
(2010)Doi:10.1021/acs.orglett.8b01377
(2018)
