124264-90-0 Usage
Uses
Used in Chemical Synthesis:
2-Nitro-N-(1-phenylethyl)benzamide is used as a key intermediate in the preparation of aralkylamides. It is involved in the propylphosphonic anhydride-mediated amidation of (aralkyl)alcohols with nitriles, which is a significant method for the synthesis of aralkylamides.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Nitro-N-(1-phenylethyl)benzamide is used as a building block for the development of new drugs. The aralkylamides synthesized using 2-NITRO-N-(1-PHENYLETHYL)BENZAMIDE have potential applications as therapeutic agents, particularly in the treatment of various diseases and disorders.
Used in Research and Development:
2-Nitro-N-(1-phenylethyl)benzamide is also utilized in research and development for the study of chemical reactions and the synthesis of novel compounds. Its unique structure and reactivity make it a valuable tool for understanding the properties and behavior of benzamides and their derivatives.
Check Digit Verification of cas no
The CAS Registry Mumber 124264-90-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,2,6 and 4 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 124264-90:
(8*1)+(7*2)+(6*4)+(5*2)+(4*6)+(3*4)+(2*9)+(1*0)=110
110 % 10 = 0
So 124264-90-0 is a valid CAS Registry Number.
124264-90-0Relevant academic research and scientific papers
Innovative approach for the synthesis of N-substituted amides from nitriles and alcohols using propylphosphonic anhydride (T3P) under solvent-free conditions
Chaithra, Nagaraju,Mantelingu, Kempegowda,Rangappa, Kanchugarakoppal S.,Rangappa, Shobith,Sandhya, Nagarakere C.,Swarup, Hassan A.
, p. 2106 - 2116 (2020/03/13)
Novel and convenient methodology for the construction of N-substituted amide derivatives have been developed from nitriles and alcohols using propylphosphonic anhydride (T3P). This methodology is an alternate approach to the synthesis of amides via Ritter reaction, which is one of the classical methods for the synthesis of N-substituted amides from nitriles and alcohols. In this approach, first T3P activates the alcohol which is then attacked by nitrile to form N-substituted amides. This methodology can also apply for the synthesis of benzhydryl ether. This developed protocol is one of the novel applications of T3P.