1242712-28-2

Upstream product

• 1253736-62-7 5-iodouridine-5'-diphosphate-α-D-galactose 
• 98-80-6 phenylboronic acid 
• 21016-94-4 5-iodouridine-5′-monophosphate 
• 58-97-9 5'-Uridylic Acid 
• 1024-99-3 5-iodouridine 
• 58-96-8 uridine 

Relevant academic research and scientific papers

A novel fluorescent probe for retaining galactosyltransferases

Glycosyltransferases (GTs) are a large class of carbohydrate-active enzymes that are involved, in both pro- and eukaryotic organisms, in numerous important biological processes, from cellular adhesion to carcinogenesis. GTs have enormous potential as mole

COMPOUNDS AND THEIR USES IN PROTEIN BINDING ASSAYS

The present invention relates to compounds and their use in competitive protein binding assays, for example for use with glycosyl transferase and/or glycoprocessing proteins. The present application also provides kits and apparatuses for use in the assays. In particular, the present invention provides a compound of the formula (I): wherein n is 1, 2 or 3; R1 is selected from -OH, -OPO3H, -OR4, -NHR4, R6; R2 and R3 are each independently selected from -H, -OH, optionally substituted -O- alkyl and -O-alkanoyl; R4 is selected from an optionally substituted mono or polysaccharide, -alkyl, -alkenyl, - alkynyl, and L-Z, where L is a linking agent and Z is a binding agent; R6 is an optionally substituted hydrocarbon group; A is either (i) a substituted heteroaryl group, the substituent on the heteroaryl group having a double bond conjugated to the heteroaryl group, or (ii) a substituted aryl group, the substituent on the aryl group having a double bond conjugated to the aryl group.