124276-79-5 Usage
General Description
1-(4-iodophenyl)cyclopropanecarbonitrile is a chemical compound that belongs to the class of cyclopropanecarbonitriles. It is formed by the substitution of a hydrogen atom in the cyclopropanecarbonitrile molecule with a 4-iodophenyl group. 1-(4-iodophenyl)cyclopropanecarbonitrile is characterized by its cyclopropane ring and nitrile functional group, which make it a versatile building block for the synthesis of various organic compounds. It can also be used as a starting material for the preparation of pharmaceuticals, agrochemicals, and materials for industrial applications due to its unique structural and chemical properties. Additionally, its 4-iodophenyl group allows for easy functionalization, making it a valuable tool in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 124276-79-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,2,7 and 6 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 124276-79:
(8*1)+(7*2)+(6*4)+(5*2)+(4*7)+(3*6)+(2*7)+(1*9)=125
125 % 10 = 5
So 124276-79-5 is a valid CAS Registry Number.
124276-79-5Relevant articles and documents
Nickel-Catalyzed Favorskii-Type Rearrangement of Cyclobutanone Oxime Esters to Cyclopropanecarbonitriles
Shuai, Bin,Fang, Ping,Mei, Tian-Sheng
, p. 1637 - 1641 (2021/10/02)
A nickel-catalyzed base-promoted rearrangement of cyclobutanone oxime esters to cyclopropanecarbonitriles was developed. The ring opening of cyclobutanone oxime esters occurs at the sterically less hindered side. A base-promoted nickelacyclobutane intermediate, formed in situ, is assumed to be involved in the formation of the product.
The diastereoselective synthesis of 2,3-diaryl-3-cyano-substituted pyrrolidines via the MgI2 mediated ring expansion of aryl cyclopropyl nitriles
Stead, Darren
supporting information, (2020/09/04)
The MgI2 mediated reaction of aryl substituted cyclopropyl nitriles with tosyl aldimines to give 2,3-diaryl-3-cyano-substituted pyrrolidines has been demonstrated. In all cases, the trans-diastereoisomer was determined to be the major product.