124288-20-6

Basic information

• Product Name: (4R,6R)-6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-naphthalen-1-yl-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one
• CAS NO: 124288-20-6
• Molecular Weight: 472.559
• Mol File: 124288-20-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R,6R)-6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-naphthalen-1-yl-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,6R)-6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-naphthalen-1-yl-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one(124288-20-6)
• EPA Substance Registry System: (4R,6R)-6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-naphthalen-1-yl-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one(124288-20-6)

Safety Data

• Hazardous Substances Data: 124288-20-6(Hazardous Substances Data)

Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 
• 114433-94-2 1-(4-Fluorophenyl)-3-isopropylpropan-1,3-dione 
• 116645-19-3 methyl 6-ethenyl-2,2-dimethyl-1,3-dioxane-4-acetate 
• 2243-55-2 1-(1-naphthyl)hydrazine 

Relevant articles and documents

Inhibitors of cholesterol biosynthesis. 2. 1,3,5-Trisbustituted [2-(tetrahydro-4-hydroxy-2-oxopyran-6-yl)ethyl]pyrazoles

A series of 1,3,5-trisubstituted pyrazole mevalonolactones were prepared and evaluated for their ability to inhibit the enzyme HMG-CoA reductase in vitro. Since previous studies suggested that the 5-(4-fluorophenyl) and 3-(1-methylethyl) substituents affo