1243047-76-8Relevant academic research and scientific papers
A Bifunctional B,N-Based Asymmetric Catalytic Nitrostyrene-Michael Addition Acting through a 10-Membered Ring Cyclic Transition State
Du, Yihao,Erdem, Safiye S.,Sari, Ozlem,Whiting, Andrew
, (2021/11/17)
The B,N-bifunctional catalyst homoboroproline has been applied to a catalytic asymmetric nitroalkene-Michael addition to β-nitrostyrene analogues, showing broad substrate tolerance, high conversions and moderate to good asymmetric induction. The ability o
New simple primary amine-thiourea organocatalysts and their application in asymmetric conjugate addition
Yu, Lu,Li, Pengfei
supporting information, p. 3697 - 3700 (2014/06/23)
A kind of simple primary amine-thiourea organocatalysts was developed. And their application in asymmetric conjugate addition of ketone to nitroalkene was investigated. In the presence of the new primary amine-thiourea, the conjugate addition of ketone to
Highly enantioselective michael addition of acetone to nitro olefins catalyzed by chiral bifunctional primary amine-thiophosphoramide catalyst
Lu, Aidang,Liu, Tao,Wu, Ronghua,Wang, Youming,Zhou, Zhenghong,Wu, Guiping,Fang, Jianxin,Tang, Chuchi
experimental part, p. 5777 - 5781 (2011/01/04)
A series of bifunctional primary amine-thiophosphoramides were synthesized, which proven to be effective organocatalysts for the asymmetric Michael reaction of acetone to both aryl and alkyl nitro olefins in the presence of phenol as a protic additive. The corresponding adducts were obtained in excellent chemical yields (up to >99%) with excellent enantioselectivities (up to 97% ee). A novel chiral phosphoramide functions well as an efficient bifunctional organocatalyst for the asymmetric Michael addition of acetone, one of the most challenge substrate in Michael addition, to nitro olefinsto afford the corresponding syntheticvaluable γ-nitro ketones in good to excellent yield with high levels of enantioselectivities (up to 97% ee, respectively).
Highly enantioselective organocatalytic conjugate addition of nitromethane to benzylidene acetones
Sznt, Gbor,Grün, Alajos,Kdas, Istvn,Bombicz, Petra
, p. 1120 - 1126 (2015/01/09)
Six active 4-aryl-5-nitro-pentan-2-ones were synthesized enantioselectively from the corresponding 5-aryl-butenones by asymmetric Michael addition of nitromethane using an imidazolidine-type enantioselective organocatalyst. The ee ratio of the products we
