124315-36-2Relevant academic research and scientific papers
Substituted diaryldiazomethanes and diazofluorenes: Structure, reactivity and stability
Davis, Philip J.,Harris, Lawrence,Karim, Aman,Thompson, Amber L.,Gilpin, Martin,Moloney, Mark G.,Pound, Matthew J.,Thompson, Claire
, p. 1553 - 1556 (2011)
The synthesis of several substituted diaryldiazomethanes and diazofluorenes, and an assessment of their structure, reactivity and stability, is reported.
Photoinduced energy- and electron-transfer processes in dinuclear ruthenium (II) and/or osmium(II) complexes connected by a linear rigid bis-chelating bridge
Cola, Luisa De,Balzani, Vincenzo,Barigelletti, Francesco,Flamigni, Lucia,Belser, Peter,Bernhard, Stefan
, p. 534 - 541 (1995)
A rigid and linear bridging ligand containing two 4,5-diazafluorene chelating units separated by an adamantane spacer (diazf-a-diazf) has been synthesized and its dinuclear complexes (4+) (Ru(II)*FAF*Ru(II)), (bpy)2Os(dia
Synthesis of new rigid, bridging ligands for the study of energy and electron-transfer reactions
Bernhard, Stefan,Belser, Peter
, p. 192 - 194 (1996)
The synthesis and characterization of rigid, rod-like, bridging ligands with an adamantane spacer and two 4,5-diazafluorene, or 1,10-phenanthroline chelating units, respectively, are described.
Cu(II)-mediated intramolecular carbene cation radical formation: Relevance to unimolecular metal - Ligand radical intermediates
Kraft, Brian J.,Eppley, Hilary J.,Huffman, John C.,Zaleski, Jeffrey M.
, p. 272 - 280 (2002)
We report the syntheses of the photochemically labile 9-diazo-4,5-diazafluorene (1) framework and the corresponding Cu(9-diazo-4,5-diazafluorene)2(NO3)2 compound (2). The X-ray structure of 2 reveals a 6-coordinate, tetragonal geometry with one nitrogen donor of an asymmetrically chelated diazafluorene in the equatorial position and the other defining the weak Jahn-Teller axis. The nitrate counterions bind in a monodentate fashion in the equatorial plane to complete the coordination sphere. Extended Hueckel calculations reveal that the unusual solid-state structure derives from the enlarged bite angle of the fluorene skeleton and steric interactions between the adjacent hydrogen atoms in the higher energy (0.45 eV) symmetrically coordinated state. This is in contrast to Cu(py)4(NO3)2 which is 1.3 eV more stable with the nitrate counterions bound along the Jahn-Telter axis. Electron paramagnetic resonance (EPR) studies in solution reveal that the nitrates dissociate to yield 6-coordinate CuN2X2N2′ structures with either a bound chloride ion (gx = 2.10, gy = 2.04, Az = 2.23, Az = 177 × 10-4 cm-1) or a mixture of counterion and solvent (gxa = 2.05, gya = 2.06, gza = 2.29, Aza = 170 × 10-4 cm-1; gxb = 2.07, gyb = 2.08, gzb = 2.34, Azb = 155 × 10-4 cm-1). Photolyses of 1 and 2 indicate loss of N2 and formation of either carbene (|D/hc| = 0.408 cm-1, |E/hc| = 0.0292 cm-1) or Cu(I)-L+ (S = 1/2, g = 2.0019) intermediates, which are identified by EPR, UV-vis, and time-dependent density functional theory methods. The results illustrate the important role redox active transition metals play in determining the nature of fundamental metal-ligand radical intermediates.
Compounds, composition, and methods for photodynamic therapy
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Page column 25, (2008/06/13)
Disclosed are novel compounds, compositions, and methods that are particularly useful in photodynamic therapy. In particular, the inventive compounds, compositions, and methods relate to the formation of cytotoxic radical species in the presence of light. Significantly, the compounds, compositions, and methods of the present invention do not require the presence of oxygen in the photodynamic therapy and, as such, rely on a unimolecular mechanism for producing the radicals. The inventive compounds, compositions, and methods can be used, for example, in the treatment of cancers as well as infections caused by microorganisms such as protozoa, fungi, bacteria, and viruses.
