124337-36-6Relevant academic research and scientific papers
Novel access to 1-substituted-benzimidazoles via benzotriazole-mediated synthesis
Rivera, Augusto,Maldonado, Mauricio,Ríos-Motta, Jaime,Navarro, Miguel Angel,González-Salas, Diego
, p. 102 - 104 (2010)
A one-pot good-yielding synthesis of 1-(alcoxymethyl)-1H-benzimidazoles and 1-((1H-benzimidazol-1-yl)methyl)-1H-benzotriazole from N1,N2-bis((1H-benzotriazol-1-yl)methyl)benzene-1,2 -diamine (3) and alcohols is described. The synthesis of 3 from macrocyclic aminal 6H,13H-5:12,7:14-dimethanedibenzo-[d,i][1,3,6,8]tetraazecine (DMDBTA, 1) and benzotriazole is also described. Both these methods are simple, isolation of the products from the reaction mixtures is easy, and the yields are good.
