1243459-56-4

Upstream product

• 868167-60-6 1-iodo-3-methoxy-5-(trifluoromethyl)benzene 
• 349-55-3 5-(trifluoromethyl)-m-anisidine 
• 401-99-0 3,5-dinitrobenzotrifluoride 
• 328-79-0 1-methoxy-3-nitro-5-trifluoromethyl-benzene 
• 868167-61-7 3-methoxy-5-(trifluoromethyl)benzonitrile 
• 557-21-1 zinc(II) cyanide 
• 1025718-84-6 3-bromo-5-(trifluoromethyl)phenol 

Downstream Products

• 1333153-81-3 3-(methoxymethoxy)-5-(trifluoromethyl)benzonitrile 
• 1333152-21-8 (Z)-isopropyl 3-(3-(3-hydroxy-5-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate 
• 1333154-09-8 (Z)-isopropyl 3-(3-(3-(methoxymethoxy)-5-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)acrylate 
• 1333153-84-6 C₁₁H₁₀F₃N₃O₂ 
• 1333153-82-4 C₁₀H₁₀F₃NO₂S 

Relevant academic research and scientific papers

CCR2 MODULATORS

Compounds are provided that are modulators of the CCR2 receptor. The compounds have the general formula (I) and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activtation of CCR2 receptors.

2,3-DIHYDROIMIDAZO[1 ,2-c] PYRIMIDIN-5(1 H)-ONE COMPOUNDS USE AS LP-PLA2 INHIBITORS

Disclosed are 2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one compounds that inhibit Lp-PLA2, processes for their preparation, compositions containing them and their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.

2,3-DIHYDROIMIDAZO[1,2-C] PYRIMIDIN-5(1H)-ONE COMPOUNDS USE AS LP-PLA2 INHIBITORS

Disclosed are 2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one compounds that inhibit Lp-PLA2, processes for their preparation, compositions containing them and their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer?s disease

NUCLEAR TRANSPORT MODULATIORS AND USES THEREOF

The invention generally relates to the field of nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to new substituted-heterocyclic azole compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g