1243541-74-3Relevant academic research and scientific papers
Synthesis of some fused heterocycles based on thieno[2,3-B]pyridine and their antimicrobial activity
El-Essawy,Hawatta,Abdel-Megied,El-Sherbeny
, p. 325 - 333 (2010)
The reaction of 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carbonitrile with ethylenediamine in the presence of a catalytic amount of carbon disulfide afforded 2-(4,5-dihydro-1H-imidazol-2-yl)-4,6-dimethylthieno-[2,3-b]pyridine-3- amine while its reaction with triethyl orthoformate followed by the reaction with hydrazine hydrate gave 4-imino-7,9-dimethylpyrido[3',2':4,5]thieno[3,2-d] pyrimidine-3(4H)-amine. These two derivatives underwent cyclocondensation reactions with commercially available reactants to afford new heterocycles containing the thieno[2,3-b]pyridine moiety. Some of the synthesized derivatives were tested for antimicrobial and antifungal activity. 2010 Springer Science+Business Media, Inc.
