124355-32-4

Basic information

• Product Name: 1-<5-O-trityl-3-(1,2,4-triazol-1-yl)-3-deoxy-β-D-arabinofuranosyl>thymine
• Synonyms: 1-<5-O-trityl-3-(1,2,4-triazol-1-yl)-3-deoxy-β-D-arabinofuranosyl>thymine
• CAS NO: 124355-32-4
• Molecular Weight: 551.602
• Mol File: 124355-32-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-<5-O-trityl-3-(1,2,4-triazol-1-yl)-3-deoxy-β-D-arabinofuranosyl>thymine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-<5-O-trityl-3-(1,2,4-triazol-1-yl)-3-deoxy-β-D-arabinofuranosyl>thymine(124355-32-4)
• EPA Substance Registry System: 1-<5-O-trityl-3-(1,2,4-triazol-1-yl)-3-deoxy-β-D-arabinofuranosyl>thymine(124355-32-4)

Safety Data

• Hazardous Substances Data: 124355-32-4(Hazardous Substances Data)

Upstream product

• 288-88-0 1,2,4-Triazole 
• 115913-84-3 1-(2,3-epoxy-5-O-trityl-β-D-lyxo-pentofuranosyl)thymine 

Downstream Products

• 124355-36-8 1-<5-O-trityl-3-(1,2,4-triazol-1-yl)-2-O-(phenoxythionocarbonyl)-3-deoxy-β-D-arabinofuranosyl>thymine 
• 124355-37-9 1-<5-O-trityl-3-(1,2,4-triazol-1-yl)-2,3-dideoxy-β-D-erythro-pentofuranosyl>thymine 
• 124355-34-6 1-<3-(1,2,4-triazol-1-yl)-3-deoxy-β-D-arabinofuranosyl>thymine 

Relevant articles and documents

Synthesis and Antiviral Activity of 3'-Heterocyclic Substituted 3'-Deoxythymidines

Various 3'-deoxythymidine analogues with an heterocyclic five-membered ring in the 3'-erythro position have been synthesized.The pyrrol-1-yl (3) and the 1,2,4-triazol-4-yl (5) compounds were synthesized from 1-(3-amino-2,3-dideoxy-β-D-erythro-pentofuranosyl)thymine.The pyrazol-1-yl (16a), imidazol-1-yl (16b), and 1,2,4-triazol-1-yl (16c) derivatives were obtained by epoxide opening of the corresponding 1-(2,3-anhydro-β-D-lyxofuranosyl)thymines followed by 2'-deoxygenation.Only the 3'-pyrrol-1-yl derivative showed marginal antiviral activity against human immunodeficiency virus.