124355-34-6 Usage
Chemical class
Nucleoside analog
Antiviral properties
Yes
Target viruses
Herpes viruses
Mechanism of action
Interferes with viral DNA replication
Commonly used form
Antiviral medications
Effective in treating
Genital herpes, shingles, and chickenpox
Chemical structure
Pyrimidine-2,4-dione ring and a triazole group
Potential side effects
Nausea, vomiting, and headache
Usage guidance
Should be used with caution under the guidance of a healthcare professional
Check Digit Verification of cas no
The CAS Registry Mumber 124355-34-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,3,5 and 5 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 124355-34:
(8*1)+(7*2)+(6*4)+(5*3)+(4*5)+(3*5)+(2*3)+(1*4)=106
106 % 10 = 6
So 124355-34-6 is a valid CAS Registry Number.
124355-34-6Relevant articles and documents
Synthesis and Antiviral Activity of 3'-Heterocyclic Substituted 3'-Deoxythymidines
Wigerinck, Piet,Aerschot, Arthur Van,Janssen, Gerard,Claes, Paul,Balzarini, Jan,et al.
, p. 868 - 873 (2007/10/02)
Various 3'-deoxythymidine analogues with an heterocyclic five-membered ring in the 3'-erythro position have been synthesized.The pyrrol-1-yl (3) and the 1,2,4-triazol-4-yl (5) compounds were synthesized from 1-(3-amino-2,3-dideoxy-β-D-erythro-pentofuranosyl)thymine.The pyrazol-1-yl (16a), imidazol-1-yl (16b), and 1,2,4-triazol-1-yl (16c) derivatives were obtained by epoxide opening of the corresponding 1-(2,3-anhydro-β-D-lyxofuranosyl)thymines followed by 2'-deoxygenation.Only the 3'-pyrrol-1-yl derivative showed marginal antiviral activity against human immunodeficiency virus.
