1243679-37-9Relevant academic research and scientific papers
A short practical approach to 24R,25-dihydroxyvitamin D3
Nicoletti, Daniel,Gregorio, Carlos,Mourino, Antonio,Maestro, Miguel
, p. 43 - 45 (2010)
A synthesis of the vitamin D3 metabolite 24R,25-dihydroxyvitamin D3 (1) by Lythgoe's Wittig-Horner approach is described. The key step of the synthesis is the stereocontrolled introduction of the 24-hydroxyl group by a palladium(0)-induced [3,3]-sigmatropic rearrangement on a 22R-allylic acetate (7).
