1243698-07-8Relevant articles and documents
A facile method for the synthesis of oxindole based quaternary α-aminonitriles via the Strecker reaction
Liu, Yun-Lin,Zhou, Feng,Cao, Jun-Jie,Ji, Cong-Bin,Ding, Miao,Zhou, Jian
supporting information; experimental part, p. 3847 - 3850 (2010/09/15)
The direct α-cyanoamination of isatins using TMSCN has been developed, which is carried out in methanol without any catalyst. A new bifunctional cinchona alkaloid-based phosphinamide catalyst 7 could promote the Strecker reaction of isatins derived ketimine with TMSCN in up to 74% ee.